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GLP-1-based therapies, such as GLP-1 receptor agonists, glucose-dependent insulinotropic polypeptide (GIP) receptor agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors, improve glucose control through various mechanisms including increased insulin secretion, slower gastric emptying, and reduced postprandial glucagon and food intake

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A lipid panel drawn at week 16 typically shows the first statistically significant triglyceride reduction compared to baseline

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Results vary, but semaglutide is generally used as part of a gradual and sustainable medical weight management plan rather than a rapid short-term approach