There were no clear differences in subject demographics or key baseline characteristics between men and women, with the exception of weight (men tended to be heavier) and smoking status (51.7 vs 26.1% and 56.1 vs 23.0% of men vs women had a history of smoking in the semaglutide and placebo groups, respectively)
Some common side effects include nausea, vomiting, diarrhea, and constipation, especially when starting or increasing the dose
They're debilitating
References Booth GL, Kapral MK, Fung K, Tu JV: Recent trends in cardiovascular complications among men and women with and without diabetes
With the explosive popularity of highly effective Anti-Obesity Medications (AOMs) like semaglutide and tirzepatide, a new concern has emerged: Are these medications causing excessive muscle wasting
Furthermore, in a phase 2 clinical trial addressing a patient group with type 2 diabetes and overweight/obesity, after 32 weeks of treatment, the cagrisema 2.4 mg group exhibited a more significant average weight loss compared to the cagrilintide 2.4 mg group or the group using semaglutide 2.4 mg alone, with reductions of 15.6%, 8.1%, and 5.1%, respectively
