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Interestingly, this enzyme enhances cysteine starvation-induced ferroptosis through activation of the GCN2-eIF2-ATF4 pathway in human triple negative breast cancer cells (60)
Baseline metabolic assessment can identify targetable phenotypes
Andreeff M , Melamed MR, Koziner B, Mertelsmann R, Hiddemann W, Chaganti RSK, Clarkson BD
136, e194752
Alexander GolBerg MD, DO is a board-certified physician with over 25 years of clinical experience in functional and regenerative medicine in New York City
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