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Cell Proliferation, 54 (3), Article e12997

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American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

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Unlike native IGF-1 which has a short half-life of only 2030 minutes IGF-1 LR3 has been modified by replacing the third amino acid with arginine and extending the peptide chain by 13 additional amino acids

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This study, which included around 6,400 patients, employed Cox regression analysis and confirmed that diabetic patients using GLP-1R agonistssuch as exenatide, liraglutide, dulaglutide, and semaglutide were less likely to receive a new glaucoma diagnosis (76)

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There is a lot of excitement around GLP-1 agonists, and it is the hope that one will end up being approved for NASH in the near future

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