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Accordingly, approved indications expanded in early 2024 to include not only reduction of hyperglycemia, but also weight management in non-diabetic patients, and even cardiovascular risk reduction in patients with elevated weight and comorbid cardiovascular disease
Con ellas se puede llegar a perder un 17% del peso inicial
by David W allace The treatment landscape for type 2 diabetes and obesity has changed dramatically with the rise of GLP-1 therapies
One works through satiety signaling
Zepbound (November 2023) for chronic weight management Real-world data : Growing post-market evidence supporting efficacy and safety in diverse populations Cardiovascular outcomes : SURPASS-CVOT trial evaluating cardiovascular endpoints Key Differences Summary# Receptor pharmacology : Retatrutide is a triple agonist (GIP/GLP-1/glucagon)
PMCID: PMC5831666
