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Unopened GLP-1 medications stored properly in the refrigerator at 36F to 46F (2C to 8C) remain effective until the expiration date printed on the packaging

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[13] Chloramphenicol has been shown to blunt reticulocyte response to cyanocobalamin, while ethanol, colchicine, and nitrous oxide interfere with cobalamin metabolism or utilization, each warranting clinician awareness when evaluating suboptimal treatment outcomes

Vitamin B12 injections are administered subcutaneously (under the skin), and can be given up to twice weekly

Patients may take semaglutide with B12 or B6, depending on their preference

It is best done in a medical setting