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Several points deserve emphasis
The methodological quality of the included studies, as assessed through the Jadad and NewcastleOttawa scales, varied from moderate to high, while the GRADE assessment indicated moderate certainty of evidence for serum vitamin B12 increase and low certainty for homocysteine reduction
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Specifically, the National Health and Nutrition Examination Survey estimated that 3.2% of adults over age 50 have seriously low levels of B12, and up to 20% may have a borderline deficiency
Each vial contains 5mg of AOD 9604 and is intended strictly for in vitro and laboratory research use only
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