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Copper is an essential trace element that participates in numerous enzymatic reactions, from mitochondrial energy production to connective-tissue crosslinking via lysyl oxidase

The study was reviewed and approved by the Ethics Committee on the Use of Animals (CEUA) of the Universidade do Extremo Sul Catarinense (UNESC), under protocol number 07/2023

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Multiple comparisons were analysed using one-way analysis of variance or two-way analysis of variance followed by Dunnetts post hoc test

doi: 10.1097/00004836-199700001-00029 97 WallaschekNReuterSSilkenatSWolfKNiklasCKayisogluOet al

Treatment effects of intranasal growth hormone releasing peptide-2 in children with short stature