GIP activation enhances insulin sensitivity, supports fat metabolism, and may improve how the body processes and stores nutrients
Its precise contribution is still an area of active research, but the clinical signal from tirzepatide larger weight loss than GLP-1 monotherapy in cross-trial comparisons is consistent with a real additive effect
As a result, this research peptide may, at least in theory, lead to an enlargement of the intestines and bubble gut, similar to those observed in bodybuilders who abuse human growth hormone injections
This dual action may have direct effects on energy expenditure in the liver, in addition to reducing appetite
Khan F, Mat A, Hogan AE, Kent BD, Eigenheer S, Corrigan MA, et al
It does so by reducing inflammation and modulating immune responses, potentially slowing the progression of diseases like rheumatoid arthritis and multiple sclerosis