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Statistical analysis was performed utilizing version 29 of the Statistical Package for the Social Sciences
doi: 10.1016/j.cmet.2008.03.006 108 LiuJCondeKZhangPLilascharoenV
Lastly, the observational design, lack of standardized outcome measures, small sample size and heterogeneity of responses to semaglutide treatment, likely due to the complex nature of obesity in PWS, reduces the generalizability of the findings to a wider population
Individual results may vary, but many people start to notice weight loss within a few weeks of starting treatment
In 2024, the ESC guidelines for elevated blood pressure and hypertension classified GLP-1 RA as therapies that have shown blood pressure-lowering properties but are awaiting further supportive evidence from cardiovascular outcomes trials prior to guideline endorsement and routine use in hypertension [49]
While these symptoms can be uncomfortable, many symptoms typically subside as the body adjusts to the medication
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