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However, Retatrutide is still investigational and carries a risk of transient increased heart rate

At the highest dose (14 mg daily), participants achieved approximately 10-12% body weight reduction compared to placebo, with meaningful improvements in cardiometabolic markers and blood glucose control

Severe bloating lasting more than 2 weeks despite dietary modifications also warrants a clinical conversation to rule out other causes and discuss whether a dose adjustment would help

However, if you lack IF (the case for people with pernicious anemia