The hazard ratio and 95% confidence interval did not reveal a significant difference between tirzepatide or insulin glargine treatment (HR, 0.74
Geroprotective and Anticarcinogenic Activity Lifetime Murine Studies Long-term studies in mice demonstrated that DSIP administration over a lifetime decreased total spontaneous tumour incidence 2.6-fold compared to untreated controls, slowed age-related switching-off of oestrous function, decreased the frequency of chromosome aberrations in bone marrow cells by 22.6%, and increased maximum lifespan by 24.1% compared to control groups a multi-parameter geroprotective profile that is among the most striking reported for any short regulatory peptide, and that has generated sustained interest in the DSIP analogue research field
Pancreas 51 , 13981403 (2022)
(New York, NY: Elsevier) 585603
Of note, many of the studies used a single-dose administration of GLP1RAs
A basic normal saline IV bag infusion that excludes extra additives, making it suitable for individuals with sensitivities