It should not be co-administered with drugs that are known to be strong CYP2C19 inhibitors, such as voriconazole and fluvoxamine
The potential molecular mechanisms underlying these effects included disturbances in redox homeostasis (as evidence by the enhanced production of ROS and reactive nitrogen species), failure of enzymatic and nonenzymatic cytoprotective mechanisms involving the glutathione system as well as nuclear factor kappa B (NF-B) and fibroblast growth factor 2-mediated pathways, and impaired mitochondrial function
The body's preferred, natural form of B12
Presented for research literature review only Suaste V et al
The optimal DSIP dosage varies wildly depending on your goals, your current sleep patterns, and how your body metabolizes this particular peptide
In terms of safety, B12 is naturally occurring in the body and therefore (even in large doses) is relatively safe