At this dose level, most people begin experiencing meaningful appetite suppression and weight loss
Understanding how dosage affects cost can save you hundreds of dollars over a treatment course
The mechanistic plausibility is strong (NNMT inhibition increases NAD+ without the gastrointestinal side effects of high-dose nicotinamide), and the short-term tolerability profile is excellent, but we mean this sincerely: if you're using this compound for durations beyond what the published trials covered, you are operating in uncharted territory
TB-500 was originally studied extensively in racehorses for injury recovery before gaining popularity in human biohacking communities
It is a long-acting analogue of amylin, a natural hormone involved in appetite and energy regulation
When one is dampened, the other can be, too