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That filing is for the combination, not for cagrilintide as a standalone product cagrilintide monotherapy remains investigational either way

MS1 scans were operated at resolution = 70,000, scan range = 851250 m/z, automatic gain control target = 1 106, and 100 ms maximum IT

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With respect to body weight, a higher baseline body-mass-index is a predictor of absolute weight reduction, albeit with substantial body weight loss even in those with a BMI 50 years with either chronic kidney disease and an eGFR of less than 60 ml/min per 1.73 m 2 or history of congestive heart failure (NY Heart Association Class II or III)

Results: The CLP-induced SAE model showed significant hippocampal damage, microglial activation, cognitive deficits, and increased levels of pro-inflammatory cytokines, ROS, and MDA