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Long-acting GLP-1 receptor (GLP-1R) mono-agonists have been developed to engage in beta cell glucose-dependent insulinotropic effect, while also acting within key feeding regions of the central nervous system to influence satiety
The International society for heart and lung transplantation guidelines for the management of pediatric heart failure: Executive summary
Moreover, intracellular meningococci induce a cellular response, such as caspase-3 activation, that participates both in the inflammatory state and in the disruption of cell-to-cell junctions
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Among the here reported anti-diabetic compounds, it looks like metformin, given its numerous anti-cancer effects which include reduction of cell growth, promotion of cell death, and reduction of cell migration as well as modulation of TC microenvironment component could be of interest for a potential repositioning
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