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It is essential to maintaining a healthy metabolism, which in turn is critical for reducing the risk of many age and lifestyle-associated disorders
Moreover, it inhibits glucagon release from the cells of the pancreas and promotes slow stomach emptying, hence giving the feeling of fullness and reduces body weight (12)
In order to suppress the nucleophilic nature of the guanidine group in arginine, it was deactivated as the monohydrochloride salt over the course of 4 steps, and then as trifluoroacetate for another 2 steps
*Correspondence: Arjola Bano, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Thus, alterations in bile acids might be associated with changes in gut microbiota
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