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L-carnitine is considered highly safe and is generally very well-tolerated by most people when taken at the recommended daily doses of 1 to 2 grams

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423 In summary, targeting lipid metabolism pathways (such as the PPAR signaling pathway and FAO), gut microbiota metabolites (such as secondary BAs), secondary BAs and their receptors (such as nuclear receptors such as FXR), and dietary and lifestyle interventions (such as the intake of n-3 and n-6 PUFAs) is a promising approach for the prevention or treatment of metabolic disorders

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