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This study innovatively focuses on the mechanism by which FOXO4-DRI induces apoptosis in senescent endothelial cells, demonstrating that it functions by activating the p53/BCL-2/Caspase-3 signaling pathway to promote selective apoptosis of these cells

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The red arrow indicates the conformational deviation of the WW domain between the two structures

Football players, hockey players, martial artists are a tiny fraction of the people who have TBI and concussion of various kinds

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PMID: 29915025 Kurutas, E.B