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This study represents the longest real-world investigation of oral semaglutide to date
Effect of Volume and Timing of Water Consumption: Single 10 mg doses of oral semaglutide (formulation R1) were administered with 50 mL or 240 mL of water after an 8-hour overnight fast and a continued fast of 4 hours post-dose in healthy subjects
However, if necessary, an unopened pen can be kept at room temperature (up to 86F) for up to 28 days before use, provided it is kept in its original carton to protect it from light
(2017) Cardiovascular safety and benefits of GLP-1 receptor agonists
Not suitable for daily at-home use
Patients should use the lowest effective dose to minimize these negative adverse effects
