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The Take-Away Its important to note that while many people report positive effects from MIC/B-12 injections, the evidence supporting these benefits is limited

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Professional Administration : While some people are trained to administer B12 injections themselves, many prefer to have them administered by a healthcare professional, which can be inconvenient and time-consuming

Topical and Nasal AOD-9604 Topical and nasal forms appear in marketing, but the FDA review found no published human exposure data for transdermal or intranasal AOD-9604

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StatPearls (US source) states, Patients generally receive lifelong intramuscular (IM) injections of vitamin B12 (typically 1000 g per month)