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Both drugs use semaglutide, a GLP-1 RA, and are manufactured by Novo Nordisk

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It has a high affinity for copper ions (Cu), forming a stable and biologically active complex that enhances coppers bioavailability and intracellular activity

This should not be viewed as a failure of the medication to work, but as a consequence of weight loss associated metabolic adaptation and hormonal response that results in slower metabolism and increased hunger

doi: 10.3390/biom11121903 216 SimonEClinoiuLFMitreaLVodnarDC

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