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Each medication works through different metabolic pathways and may be appropriate for different patients
The mechanisms of DSPN are not fully understood but involve downstream injurious pathways associated with hyperglycaemia, dyslipidaemia and microvascular disease leading to neuronal inflammation, oxidative stress, mitochondrial dysfunction and cell death
Our bodys response to this focused energy delivery is neo-collagenesis, or the stimulation of new collagen
That landscape shifted in December 2025, when the U.S
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