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Energy Environ Sci
These resistance mechanisms contribute to diminished treatment responsiveness, necessitating the development of precision-based therapies to overcome such barriers (Krishnan et al., 2025b)
Multidisciplinary Digital Publishing Institute (MDPI)
Table 1 Strategies available for the management of euthyroid patients with Hashimoto thyroiditis with persistent symptoms and their related mechanisms
Alpha-lipoic acid Alpha-lipoic acid is a scavenger of free radicals and also aids in the regeneration of glutathione
The gentle ramp from 0.25 mg up to 2.4 mg mirrors the phase 2 dose-finding schedule that achieved meaningful weight loss while keeping nausea and other gastrointestinal effects manageable [1] [4]
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