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While B12 is generally safe, caution is needed in specific clinical situations: Lebers Disease (Hereditary Optic Neuropathy): B12 injections are generally contraindicated or should be used with extreme caution, as they may potentially aggravate optic atrophy in this rare condition

This formulation is of interest in scientific research investigating mechanisms related to energy metabolism, endurance, and cellular efficiency

It is light sensitive, so store it in a dark place

The recommendation: remove the vial from refrigeration 15-20 minutes before drawing the dose, or warm the filled syringe in your palm for 60 seconds before injecting

An abscess is the body's way of trying to heal from an infection

So it can take 2-5 years before you see signs of B12 deficiency