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A peer-reviewed study in the Journal of Cosmetic Dermatology found GHK-Cu reduced wrinkle volume by 55.8% and outperformed Matrixyl 3000 by 31.6% in wrinkle volume reduction

Also, high-dose B12 has been linked to acneiform eruptions in some case reports and reviews (Bahbouhi et al., 2023) as described in the PubMed record

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