Saunders says when her patients have tried to indulge in big meals after skipping a dose, they often learn that overeating can still provoke punishing side effects: Eating heavy foods or large portions while on semaglutide or tirzepatide can lead to heartburn, nausea, and vomiting
Brian Reid
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6.2 GLP-1 role in metabolic stability GLP-1 plays a key role in maintaining metabolic stability, particularly in critical conditions such as sepsis, where the organism often enters a catabolic state with disturbed glycemic regulation
Eringa EC, Bakker W, van Hinsbergh VWM