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[50] PA is identified with a high MCV (macrocytic anemia) and a normal MCHC (normochromic anemia)

It is not a willpower problem

In the SURMOUNT-1 trial of tirzepatide, participants on the 15 milligram dose lost an average of 20.9 percent of their body weight over 72 weeks, while the STEP 1 trial of once-weekly semaglutide reported about 14.9 percent over 68 weeks

After 50, the body naturally loses muscle mass at a rate of 1-2% per year (sarcopenia), and adding semaglutide-driven calorie restriction on top of age-related muscle loss can be devastating

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The challenge is knowing where to start, tracking whether you are actually progressing, and staying consistent