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5-Amino-1MQ inhibits the enzyme NNMT (nicotinamide N-methyltransferase), which is involved in NAD+ metabolism within fat cells

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The inhibition of fatty acid oxidation in the liver re-routes LCFAs into triglycerides (TAGs)

Additionally, B12 is water-soluble, meaning that the body naturally filters out what it has no use for

Studies have examined how these metabolic changes affect various cellular processes including energy metabolism and gene expression