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Always consult your GP or pharmacist before starting any laxative regimen, particularly if you have inflammatory bowel disease, intestinal obstruction, severe abdominal pain, or are pregnant or breastfeeding

There are also several distinctions

no fixed modifications

This dual effect on both sides of the energy balance equation is why retatrutide produced the highest weight loss percentages of any single-agent trial

"We're very interested to see how the story with these drugs unfolds and whether we might actually see a beneficial effect that persists long term in terms of not only weight loss but substance use," Steffen said

Available at: (Accessed: 27th August 2015)