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The medications that started as a treatment for diabetes, regulating patients insulin and blood sugar with a weekly injection, have evolved into what some are calling wonder drugs
Rhee SG (2006) Cell signaling
therefore, it is reasonable to assume that drugs targeting TGR will have a different mechanism of action than praziquantel
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Melanotan-1: Well-tolerated in trials
In addition, one must gain FDA approval by clinically demonstrating that the delivery of the microbe-encapsulated GLP-1 through this oral route leaves the drug molecule itself unchanged (with no post-translational modifications), that it has a similar pharmacokinetic profile to the reference molecule, and that it shows no adverse effects
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