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Cancer 124 , 192202 (2018)
Given the rising prevalence of childhood obesity and Food and Drug Administration (FDA) approval of these medications after the age of 12 in the United States, this trend of increased use is not surprising, but access and usage of these medications vary widely
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Participants in the Phase 3 TRIUMPH-4 trial taking 12mg at 68 weeks lost an average of 28.7% of their body weight the most significant result reported at that stage for any obesity-related compound to date
Some patients report that glycine-containing formulations are gentler on the stomach, particularly during the initial weeks of treatment when gastrointestinal side effects tend to be most pronounced
