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13 We hypothesize that a subset of children with ASD manifest biomarkers of abnormal mitochondrial fatty-acid metabolism that are similar to those reported in the PPA rodent model of ASD

1 : 88100 Cullis PR, DeKruijff B

Cell 187 , 166183.e125 (2024)

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In cardiovascular disease, LOX expression is upregulated, which in turn promotes lipid peroxidation and ferroptosis (Fratta Pasini et al., 2023)

These approaches work well when speed matters and when there is defined endpoint for treatment