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Protocol 2: Perimenopause + significant weight gain Goal: Lose 20-30+ lbs gained during perimenopause Aggressive stack: Semaglutide: 1-2mg weekly (or Tirzepatide 5-10mg) CJC-1295 + Ipamorelin: 200mcg each before bed BPC-157: 250mcg twice daily Selank: As needed for mood Why this combination: Semaglutide: Powerful weight loss, appetite control CJC + Ipamorelin: Preserve muscle during weight loss, maintain metabolism BPC-157: Support gut health, reduce inflammation Selank: Manage emotional eating Expected results: 20-30 lbs lost in 4-6 months Improved body composition (fat loss, muscle preservation) Better metabolic health Sustained results Timeline: Month 1: 5-8 lbs lost Month 2-3: 10-15 lbs lost Month 4-6: 20-30 lbs lost Ongoing: Maintenance Cost: $400-600/month Use our peptide cost calculator to budget and peptide stack calculator to plan combinations

Kidney and cardiovascular effectiveness of SGLT2 inhibitors vs GLP-1 receptor agonists in type 2 diabetes

Regular follow-ups with healthcare providers can also help

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doi:10.5935/1518-0557.20180014 89