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The stomach area often responds quickly, with a reduction in visceral and subcutaneous fat. These hormone-sensitive areas can be hard to manage with exercise alone, but semaglutide helps mobilize stored fat here too
127,128,129,130 The resulting glutathione persulphide is a substrate for either persulphide dioxygenase, which oxidises the sulphane sulphur yielding sulphite and glutathione, or rhodanese, which generates thiosulphate
Some people see a visible change in 6 to 8 weeks, while others may take up to 12 weeks
Theoretical concerns have been raised regarding GLP-1 medicines and cancer risk, primarily based on animal studies
A practical approach is to set hourly reminders to sip 46 ounces of tea or water, rather than trying to drink 16 ounces in one sitting, which often feels uncomfortable
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