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For most individuals, the significant health benefits of weight lossincluding improved heart health, better blood sugar control, and increased mobilityfar outweigh the very small statistical risk of appendicitis

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Tirzepatide (brand name Mounjaro) works by mimicking two hormonesGLP-1 and GIPthat tell your brain you're full and slow how fast your stomach empties food

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NOTE: Troglitazone was removed from the US market in response to FDA concerns in March 2000

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,

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Neither drug should be used by patients with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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Serious reactions that warrant immediate care include large bruises (larger than a quarter), bruises accompanied by severe pain or warmth, signs of infection (redness, pus, fever), or bruising that worsens after 48 hours

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