For severe deficiency, the AAFP recommends loading doses typically daily or every other day for one to two weeks followed by monthly maintenance injections
& Parthasarathy, S
Make sure any clinic you choose uses pharmaceutical-grade B12 and is staffed by licensed medical professionals
Other groups who may benefit include: Patients following gastric surgery (gastrectomy, bariatric procedures) where intrinsic factor production or absorption sites are compromised Individuals with malabsorption disorders such as Crohn's disease, coeliac disease, or chronic pancreatitis Strict vegans and vegetarians with dietary insufficiency, though oral supplementation is usually tried first Elderly patients with atrophic gastritis or reduced gastric acid production Patients on long-term metformin or proton pump inhibitors, which can impair B12 absorption [6] [8] Individuals with nitrous oxide exposure (recreational or medical), which can cause functional B12 deficiency Diagnosis typically involves serum B12 measurement, with levels below approximately 148 pmol/L (though thresholds vary between laboratories) generally indicating deficiency
Because this product contains benzyl alcohol, it should not be used in newborns or in people who are sensitive to benzyl alcohol
Joint and Cartilage Repair Key Findings: AOD-9604 supports the regeneration of cartilage tissue and reduces inflammation in joint structures