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In terms of long-term side effects, the data suggests that any issues tend to appear early on

Although Grx are mainly responsible for deglutathionylation reactions, recent evidence has indicated a role for Grx in protein glutathionylation, mediated by the stabilization of a GSH thiyl radical which is then subsequently transferred to an available protein thiol (Starke et al., 2003)

WMD = 2.30 kg, 95% CI 0.53 to 4.07, P = 0.01, 2 = 0.0%

Zhang, J., Wang, B., Yuan, S., He, Q

doi: 10.3390/v10080392 144 KlokF

Patient initiation and maintenance of GLP-1 RAs for treatment of obesity: a narrative review and practical considerations for primary care providers