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I usually notice an uptick in my energy levels a few days after my doc gives the shot." Zoe Macfarlane, 43, Los Angeles Try it: Needles bypass the gut to deliver the nutrient straight to the muscle, so you may feel the effects as soon as the "juice" goes in or up to a few days after

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Vitamin B 12 deficiency resulting from inadequate dietary intake is the easiest to treat

If you have a severe deficiency, they may offer you a vitamin B12 injection

I store the B12 in the door of my frig, so they're about 39 degrees F, and in total darkness virtually all the time