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Expect reduced appetite, possible nausea (usually mild and temporary), changes in bowel habits, and a shift in food preferencesmany patients report that previously favorite high-sugar or high-fat foods become less appealing

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10.1016/0026-0495(92)90171-6 Metabolism 58 MarinoniE.LetiziaC.CiardoF.CoronaG.MoscariniMDi IorioR

In the context of cancer progression, MAPK signals are involved in various activities of cancer cells, including proliferation, apoptosis and immune escape