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Biotransformation can temporarily increase reactivity
Taken orally, glutathione has inherently low bioavailability as it faces two key obstacles: the strong acidity of gastric juices and the action of a liver enzyme called gamma-glutamyltranspeptidase (GGT) which catalyses the first stage of its breakdown (8)
Bremelanotide, on the other hand, does not have the same contraindication with nitrates since it doesnt cause vasodilation-induced hypotension
Eating smaller, more frequent meals and staying hydrated can reduce early nausea
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