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NO/cGMP pathway, RhoA/ROCK pathway, endothelium-derived vasoactive factors, testosterone level, oxidative stress, programmed cell death, etc
Plan for escalation: Stock up on bland foods and clear liquids before dose increases
However, periodic breaks may help maintain receptor sensitivity
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10.1016/j.diabres.2018.02.023 20 ConcaT.Saint-PierreC.HerskovicV.SeplvedaM.CapurroD.PrietoF.et al (2018)
Blood was sampled before meal ingestion (time 0 min) and 30, 60, and 120 min after meal ingestion and plasma OXM was analyzed as described 65
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