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LEO alleviates T2DM by remodeling the gut microbiota ecosystem, enhancing butyrate biosynthesis, and activating an MPC2-dependent mitochondrial energy metabolism pathway to reverse GLP-1 secretory dysfunction in intestinal L cells
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Berg suggests natural GLP-1 agonists such as berberine and panax ginseng
doi: 10.1056/NEJMoa1212914 242 PownallHJSchwartzAVBrayGABerkowitzRILewisCEBoykoEJet al
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