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How Genetic Predispositions Inform Your Personalized Safety Conversation Genetic variants in GLP-1 receptor (GLP1R rs6923761) and glucose-dependent insulinotropic peptide receptor (GIPR rs1800437) influence how your body's GLP-1 signaling pathways respond

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NNT CKM was calculated based on the same events as for NNT EXTENDED , in addition to the following clinical and subclinical events that are relevant from a holistic, CKM syndrome perspective: progression to biochemical diabetes (at least one post randomization HbA 1c 6.5%), and a 5-point nephropathy composite