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GHK-Cu exists as a 1:1 copper(II):peptide complex in which the Cu(II) ion is coordinated by the glycine terminal amino group, the amide nitrogen between glycine and histidine, the histidine imidazole nitrogen, and the lysine side chain amino group in a square planar arrangement
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In a parallel-arm, open-label human study, twelve healthy subjects ( n 6 per group) received a single oral dose of either LipoDuo or plain glutathione (1 g), and plasma glutathione levels were monitored over 24 h using LC-MS/MS
However, caution is warranted here
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