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L-carnitine affects glycemic markers, hyperglycemia, and insulin resistance ( via a number of different pathways, including the following: (1) Controlling the pyruvate dehydrogenase complex's (PDHC) activity and the intramitochondrial acetyl-CoA/CoA ratio

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[109] demonstrated that a shiitake-rich diet significantly increased plasma ergothioneine levels, enhancing OCTN1-mediated transport of gabapentin

It interacts with amylin receptors and calcitonin receptors, which are widely studied for their roles in appetite and energy balance

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