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The SURPASS-CVOT trial, which directly compared these two medications in over 13,000 people with type 2 diabetes, found that tirzepatide produced approximately 12% weight loss compared with 5% for dulaglutide over 4 years
It does mean the risk is clinically important enough that it should not be brushed aside
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trials ran to 68 weeks with continued, progressive weight loss [2]
With the pill, you dont get the same blood concentration levels and it doesn't stick around as long, says Ard
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