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Central nervous system effects include appetite suppression through actions on hypothalamic centers that regulate hunger and satiety
For details, see: Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial
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Additional proteins associated with lipid droplets (LD) in adipocytes participate in the ABHD5-mediated regulation of ATGL
14,15 Extreme stress and eating disorders can disrupt hypothalamic signaling, leading to ovarian dysfunction and anovulation
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