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Pharmacol Res Perspect (2021) 9
Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
The established adverse effect profile, based on clinical trial data submitted to regulatory authorities such as the MHRA and EMA, predominantly features gastrointestinal symptoms
Is GHK-Cu as good as minoxidil for regrowth
Importantly, these macromolecular systems enable multimodal intervention within a single formulation, supporting the development of personalized nanotherapeutics
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