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Bile excretion was studied in six SD rats with BDC
These properties were combined in the design of the unimolecular triagonist MAR423 with promising results in animal models which have been taken forward to an ongoing phase 1 trial [60]
Studies suggest that supraphysiological doses of exogenous GLP-2 has a significant inhibitory effect on bone resorption, however the specific mechanism by which GLP-2 influences bone metabolism remains unknown
10.1016/j.joca.2013.01.014 Osteoarthr
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